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Sildenafil can be a strong and selective inhibitor of cGMP-precise phosphodiesterase style 5 (PDE5), which can be to blame for degradation of cGMP in the corpus cavernosum. The molecular construction of sildenafil is similar to that of cGMP and acts as being a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and in